Guanosine 5'-diphosphate (sodium), 96% (HPLC)
Product Specifications
UNSPSC Description
Guanosine 5'-diphosphate (sodium), 96% (HPLC) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K+ channel. Guanosine 5'-diphosphate sodium, Type I, 96% (HPLC) is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate (sodium), 96% (HPLC) can be used in the research of inflammation, such as anemia of inflammation (AI)[1][2].
Target Antigen
Endogenous Metabolite; Potassium Channel
Type
Biochemical Assay Reagents
Related Pathways
Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/guanosine-5-diphosphate-sodium.html
Purity
99.88
Solubility
H2O : ≥ 100 mg/mL
Smiles
O=P(OP(O)(O[Na])=O)(O)OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N=C(N)NC3=O)=C3N=C2)O1
Molecular Weight
465.18
References & Citations
[1]S Kajioka, et al. Guanosine diphosphate activates an adenosine 5'-triphosphate-sensitive K+ channel in the rabbit portal vein. J Physiol. 1991 Dec;444:397-418. |[2]Angmo S, et al. Identification of Guanosine 5'-diphosphate as Potential Iron Mobilizer: Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway. Sci Rep. 2017 Jan 5;7:40097.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-113066C/Guanosine-5-diphosphate-sodium-96-HPLC-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-113066C/Guanosine-5-diphosphate-sodium-96-HPLC-SDS-MedChemExpress.pdf
Clinical Information
Phase 3
CAS Number
43139-22-6
Available Sizes
Curated Selection
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