Benserazide-d3 (hydrochloride)
Benserazide-d3 (hydrochloride) is the deuterium labeled Benserazide hydrochloride. Benserazide hydrochloride (Serazide) is an aromatic L-amino acid decarboxylase (AADC) and L-DOPA decarboxylase inhibitor. Benserazide hydrochloride is also a PKM2 inhibitor. Benserazide hydrochloride directly binds to and blocks PKM2 enzyme activity, leading to inhibition of aerobic glycolysis concurrent up-regulation of OXPHOS. Benserazide hydrochloride can be used for the study of Parkinson's disease and melanoma[1][2][3].
Product Specifications
Product Name Alternative
Ro 4-4602-d3 (hydrochloride)
UNSPSC
12352005
Target
Isotope-Labeled Compounds; Pyruvate Kinase
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cancer; Neurological Disease
Solubility
10 mM in DMSO
Smiles
O=C(C(C([2H])([2H])O)([2H])N)NNCC1=CC=C(C(O)=C1O)O.Cl
Molecular Formula
C10H13D3ClN3O5
Molecular Weight
296.72
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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