ODN 6016

ODN 6016 is a CpG-A oligonucleotides. ODN 6016 can induce IFN-α production, can be used for researching immune disorders including immunodeficiency caused by HIV-1. ODN 6016 sequence: T-sp-C-G-A-C-G-T-C-G-T-G-G-sp-G-sp-G-sp-G[1][2].

Product Specifications

CAS Number

[1271731-64-6]

UNSPSC

12352208

Target

IFNAR

Type

Oligonucleotides

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/odn-6016.html

Purity

94.95

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

[DNA,d(T-sp-C-G-A-C-G-T-C-G-T-G-G-sp-G-sp-G-sp-G)?]

Molecular Weight

4729.30

References & Citations

[1]Ries M, et al. Identification of novel oligonucleotides from mitochondrial DNA that spontaneously induce plasmacytoid dendritic cell activation. J Leukoc Biol. 2013 Jul;94 (1) :123-35.|[2]Tennert K, et al. Elevated CD40 ligand silences α interferon production in an HIV-related immune reconstitution inflammatory syndrome. AIDS. 2013 Jan 14;27 (2) :297-9.