ODN 6016
Product Specifications
UNSPSC Description
ODN 6016 is a CpG-A oligonucleotides. ODN 6016 can induce IFN-α production, can be used for researching immune disorders including immunodeficiency caused by HIV-1. ODN 6016 sequence: T-sp-C-G-A-C-G-T-C-G-T-G-G-sp-G-sp-G-sp-G[1][2].
Target Antigen
IFNAR
Type
Oligonucleotides
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/odn-6016.html
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
[DNA, d(T-sp-C-G-A-C-G-T-C-G-T-G-G-sp-G-sp-G-sp-G)?]
Molecular Weight
4729.30
References & Citations
[1]Ries M, et al. Identification of novel oligonucleotides from mitochondrial DNA that spontaneously induce plasmacytoid dendritic cell activation. J Leukoc Biol. 2013 Jul;94(1):123-35.|[2]Tennert K, et al. Elevated CD40 ligand silences α interferon production in an HIV-related immune reconstitution inflammatory syndrome. AIDS. 2013 Jan 14;27(2):297-9.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-150747/ODN-6016-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-150747/ODN-6016-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1271731-64-6
Available Sizes
Curated Selection
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