Sanggenon A

Sanggenon A (Sanggenone A) exerts anti-inflammatory effects by regulating NF-κB and HO-1/Nrf2 signaling pathways in BV2 and RAW264.7 cells. Sanggenon A markedly inhibits the Lipopolysaccharide (LPS; HY-D1056) -induced production of nitric oxide[1].

Product Specifications

CAS Number

[76464-71-6]

Product Name Alternative

Sanggenone A

UNSPSC

12352005

Target

Keap1-Nrf2; NF-κB

Type

Natural Products

Related Pathways

NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/sanggenon-a.html

Solubility

10 mM in DMSO

Smiles

C/C(C)=C\C[C@@]12[C@@](C(C3=C(O)C(C=CC(C)(O4)C)=C4C=C3O1)=O)(OC5=CC(O)=CC=C52)O

Molecular Formula

C25H24O7

Molecular Weight

436.45

References & Citations

[1]Wonmin Ko, et al. Kuwanon T and Sanggenon a Isolated from Morus alba Exert Anti-Inflammatory Effects by Regulating NF-κB and HO-1/Nrf2 Signaling Pathways in BV2 and RAW264.7 Cells. Molecules. 2021 Dec 16;26 (24) :7642.