Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

PD-1/PD-L1-IN-10

PD-1/PD-L1-IN-10 (compound B2) is an orally active PD-1/PD-L1 inhibitor (IC50 of 2.7 nM) with potent anticancer efficacy[1].

Product Specifications

CAS Number

[2487550-41-2]

UNSPSC

12352005

Target

Apoptosis; PD-1/PD-L1

Type

Reference compound

Related Pathways

Apoptosis; Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pd-1-pd-l1-in-10.html

Purity

99.61

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC1=C(C=CC=C1C2=CC=CC=C2)COC3=C(C=C(C(OCC4=CC(C#N)=CC=C4)=C3)CN[C@H](C(O)=O)C(O)C)[N+]([O-])=O

Molecular Formula

C33H31N3O7

Molecular Weight

581.62

References & Citations

[1]Yiqiang OuYang, et al. Design, Synthesis, and Evaluation of o- (Biphenyl-3-ylmethoxy) nitrophenyl Derivatives as PD-1/PD-L1 Inhibitors with Potent Anticancer Efficacy In Vivo. J Med Chem. 2021 May 26.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

More Discoveries

Explore Other Products

Browse additional items from our catalog

7-((2-Aminopropyl-1,1,2,3,3,3-D₆)amino)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid Hydrochloride
TRC-A629301-25MG 25 mg

7-((2-Aminopropyl-1,1,2,3,3,3-D₆)amino)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid Hydrochloride

Sign In for Pricing
View Details
CD38 (ADP Ribosyl Cyclase I) Recombinant Rabbit Monoclonal Antibody [Clone CD38/7017R]
MBS4382402-01 0.02 mg (With BSA & Azide at 0.2mg/mL)

CD38 (ADP Ribosyl Cyclase I) Recombinant Rabbit Monoclonal Antibody [Clone CD38/7017R]

Sign In for Pricing
View Details
CD38 (ADP Ribosyl Cyclase I) Recombinant Rabbit Monoclonal Antibody [Clone CD38/7017R]
MBS4382402-02 0.1 mg (With BSA & Azide at 0.2mg/mL)

CD38 (ADP Ribosyl Cyclase I) Recombinant Rabbit Monoclonal Antibody [Clone CD38/7017R]

Sign In for Pricing
View Details
CD38 (ADP Ribosyl Cyclase I) Recombinant Rabbit Monoclonal Antibody [Clone CD38/7017R]
MBS4382402-03 0.1 mg (Without BSA & Azide at 1mg/mL)

CD38 (ADP Ribosyl Cyclase I) Recombinant Rabbit Monoclonal Antibody [Clone CD38/7017R]

Sign In for Pricing
View Details
CD38 (ADP Ribosyl Cyclase I) Recombinant Rabbit Monoclonal Antibody [Clone CD38/7017R]
MBS4382402-04 5x 0.1 mg (With BSA & Azide at 0.2mg/mL)

CD38 (ADP Ribosyl Cyclase I) Recombinant Rabbit Monoclonal Antibody [Clone CD38/7017R]

Sign In for Pricing
View Details
CD38 (ADP Ribosyl Cyclase I) Recombinant Rabbit Monoclonal Antibody [Clone CD38/7017R]
MBS4382402-05 5x 0.1 mg (Without BSA & Azide at 1mg/mL)

CD38 (ADP Ribosyl Cyclase I) Recombinant Rabbit Monoclonal Antibody [Clone CD38/7017R]

Sign In for Pricing
View Details