Mps1-IN-3

Mps1-IN-3 is a potent and selective MPS1 kinase inhibitor, with an IC50 of 50 nM.

Product Specifications

CAS Number

[1609584-72-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Mps1

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mps1-in-3.html

Purity

99.73

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC1CCN(C2=CC=C(NC3=NC(NC4=CC=CC=C4S(=O)(C(C)C)=O)=C5N=CNC5=N3)C(OC)=C2)CC1

Molecular Formula

C26H31N7O4S

Molecular Weight

537.63

Precautions

H302, H315, H319, H335

References & Citations

[1]Tannous BA, et al. Effects of the selective MPS1 inhibitor MPS1-IN-3 on glioblastoma sensitivity to antimitotic drugs. J Natl Cancer Inst. 2013 Sep 4;105 (17) :1322-31.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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