Mps1-IN-3
Mps1-IN-3 is a potent and selective MPS1 kinase inhibitor, with an IC50 of 50 nM.
Product Specifications
CAS Number
[1609584-72-6]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Mps1
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mps1-in-3.html
Purity
99.73
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1CCN(C2=CC=C(NC3=NC(NC4=CC=CC=C4S(=O)(C(C)C)=O)=C5N=CNC5=N3)C(OC)=C2)CC1
Molecular Formula
C26H31N7O4S
Molecular Weight
537.63
Precautions
H302, H315, H319, H335
References & Citations
[1]Tannous BA, et al. Effects of the selective MPS1 inhibitor MPS1-IN-3 on glioblastoma sensitivity to antimitotic drugs. J Natl Cancer Inst. 2013 Sep 4;105 (17) :1322-31.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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