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Mps1-IN-3

Product Specifications

UNSPSC Description

Mps1-IN-3 is a potent and selective MPS1 kinase inhibitor, with an IC50 of 50 nM.

Target Antigen

Mps1

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage;Cytoskeleton

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mps1-in-3.html

Purity

99.67

Solubility

DMSO : 31.25 mg/mL (ultrasonic;warming;heat to 60°C)

Smiles

OC1CCN(C2=CC=C(NC3=NC(NC4=CC=CC=C4S(=O)(C(C)C)=O)=C5N=CNC5=N3)C(OC)=C2)CC1

Molecular Weight

537.63

References & Citations

[1]Tannous BA, et al. Effects of the selective MPS1 inhibitor MPS1-IN-3 on glioblastoma sensitivity to antimitotic drugs. J Natl Cancer Inst. 2013 Sep 4;105(17):1322-31.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-12401/Mps1-IN-3-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-12401/Mps1-IN-3-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

1609584-72-6

Available Sizes

Curated Selection

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