STL427944
STL427944 is a potent and selective FOXM1 inhibitor. STL427944 has the potential for the research of overcoming tumor chemoresistance and improving the efficacy of treatment with conventional cancer drug[1].
Product Specifications
CAS Number
292028-62-7
UNSPSC
12352005
Target
Autophagy
Type
Reference compound
Related Pathways
Autophagy
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/stl427944.html
Smiles
O=C(C1=CC=CO1)OC2=CC=CC(/C=N/NC3=NC(N4CCOCC4)=NC(NC5=CC=CC=C5)=N3)=C2
Molecular Formula
C25H23N7O4
Molecular Weight
485.49
References & Citations
[1]Chesnokov MS, et al. Novel FOXM1 inhibitor identified via gene network analysis induces autophagic FOXM1 degradation to overcome chemoresistance of human cancer cells. Cell Death Dis. 2021 Jul 14;12 (7) :704.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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