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Purified Anti-Human CD11a Antibody[HI111]

Product Specifications

Background

CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50) .

Abbreviation

CD11a

Gene ID

3683

UniProt

P20701

Host

Mouse

Reactivity

Human

Target

CD11 antigen-like family member A; CD11a; Integrin alpha-L; Itgal; LFA-1A; Ly-15; Lymphocyte antigen 15

Clonality

Monoclonal

Clone

HI111

Conjugation

Unconjugated

Applications

FCM

Field of Research

Cell Adhesion; Cell Biology; Costimulatory Molecules; Immunology; Innate Immunity; Neuroinflammation; Neuroscience

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Product Datasheet

https://789.bio/ea/whlus8

Product MSDS

https://789.bio/eb/Z9ZD40

Recommended Usage

6

Isotype

Mouse IgG1, κ

Available Sizes

Curated Selection

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