Thiobenzanilide 63T
Thiobenzanilide 63T (63T) is a small molecule that selectively induces cancer cell death in a caspase-independent pathway. Thiobenzanilide 63T induces reactive oxygen species and lipid peroxidation. Thiobenzanilide 63T demonstrates strong cytotoxic activity against a lung-derived cancer cell line. Thiobenzanilide 63T decreases the expression of heme oxygenase (HO-1) in A549 cells[1][2].
Product Specifications
CAS Number
1270966-08-9
UNSPSC
12352005
Target
Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/thiobenzanilide-63t.html
Smiles
FC1=C(F)C(F)=CC(C(NC2=C(NC(C3=CC(F)=C(C(F)=C3)F)=S)C=CC=C2)=S)=C1
Molecular Formula
C20H10F6N2S2
Molecular Weight
456.43
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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