PNT6555
PNT6555 is a fibroblast activation protein-α (FAP) inhibitor. PNT6555 has antitumor activity. PNT6555 can be used for imaging of FAP-positive tumors[1].
Product Specifications
CAS Number
2715113-34-9
UNSPSC
12352005
Target
FAP
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pnt6555.html
Purity
96.55
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
OC(CN1CCN(CC(NCC2=CC=C(C(N[C@@H](C(N3[C@H](B(O)O)CCC3)=O)C)=O)C=C2)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1)=O
Molecular Formula
C31H48BN7O11
Molecular Weight
705.56
References & Citations
[1]Poplawski S E, et al. Preclinical Development of PNT6555, a Boronic Acid–Based, Fibroblast Activation Protein-α (FAP) –Targeted Radiotheranostic for Imaging and Treatment of FAP-Positive Tumors [J]. Journal of Nuclear Medicine, 2023.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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