PNT6555

PNT6555 is a fibroblast activation protein-α (FAP) inhibitor. PNT6555 has antitumor activity. PNT6555 can be used for imaging of FAP-positive tumors[1].

Product Specifications

CAS Number

[2715113-34-9]

UNSPSC

12352005

Target

FAP

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pnt6555.html

Purity

96.55

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

OC(CN1CCN(CC(NCC2=CC=C(C(N[C@@H](C(N3[C@H](B(O)O)CCC3)=O)C)=O)C=C2)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1)=O

Molecular Formula

C31H48BN7O11

Molecular Weight

705.56

References & Citations

[1]Poplawski S E, et al. Preclinical Development of PNT6555, a Boronic Acid–Based, Fibroblast Activation Protein-α (FAP) –Targeted Radiotheranostic for Imaging and Treatment of FAP-Positive Tumors [J]. Journal of Nuclear Medicine, 2023.