ARUK2001607

ARUK2001607 is a selective phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) inhibitor with a Kd of 7.1 nM. ARUK2001607 shows high selectivity over other >150 kinases[1].

Product Specifications

CAS Number

[2924824-56-4]

UNSPSC

12352005

Target

PI5P4K

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/aruk2001607.html

Purity

99.73

Solubility

DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CC1=CC2=C(N=CN=C2S1)NC3=CC=C(C=C3)S(C)(=O)=O

Molecular Formula

C14H13N3O2S2

Molecular Weight

319.40

References & Citations

[1]Timothy P C Rooney, et al. The Identification of Potent, Selective, and Brain Penetrant PI5P4Kγ Inhibitors as In Vivo-Ready Tool Molecules. J Med Chem. 2022 Dec 14.