Prolyl endopeptidase inhibitor 2
Prolyl endopeptidase inhibitor 2 (Compound 8) was a proline endopeptidase (PEP) inhibitor with IC50 value 31.11 μM. Prolyl endopeptidase inhibitor 2 can be used in the study of neurodegenerative diseases[1].
Product Specifications
CAS Number
2362592-81-0
UNSPSC
12352005
Target
Prolyl Endopeptidase (PREP)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/prolyl-endopeptidase-inhibitor-2.html
Purity
98.37
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(Br)C=C1)CN2N=NC(CN(C3=CC=CC=C34)C5=C4C=C(C6=CC7=C(N(CC8=CN(CC(C9=CC=C(Br)C=C9)=O)N=N8)C%10=CC=CC=C%107)C=C6)C=C5)=C2
Molecular Formula
C46H32Br2N8O2
Molecular Weight
888.61
References & Citations
[1]Ullah S, et al. Exploring bi-carbazole-linked triazoles as inhibitors of prolyl endo peptidase via integrated in vitro and in silico study. Sci Rep. 2024 Apr 1;14 (1) :7675.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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