FtsZ-IN-11
FtsZ-IN-11 (compound B6) is a FtsZ inhibitor with the IC50 of 235 μM against XooFtsZ. FtsZ-IN-11 can interact with XooFtsZ and inhibit its GTPase activity, leading to bacterial cell elongation and even death[1].
Product Specifications
CAS Number
[3042897-74-2]
UNSPSC
12352211
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ftsz-in-11.html
Smiles
CCCCCCCCCNC(CC1)CCN1C2=NC=NC3=C2C=CN3
Molecular Formula
C20H33N5
Molecular Weight
343.51
References & Citations
[1]Li T, Zhou Y, Fu X, et al. Identification of novel 4-substituted 7H-pyrrolo[2,3-d]pyrimidine derivatives as new FtsZ inhibitors: Bioactivity evaluation and computational simulation. Bioorg Chem. 2024;150:107534.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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