FtsZ-IN-11

FtsZ-IN-11 (compound B6) is a FtsZ inhibitor with the IC50 of 235 μM against XooFtsZ. FtsZ-IN-11 can interact with XooFtsZ and inhibit its GTPase activity, leading to bacterial cell elongation and even death[1].

Product Specifications

CAS Number

[3042897-74-2]

UNSPSC

12352211

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ftsz-in-11.html

Smiles

CCCCCCCCCNC(CC1)CCN1C2=NC=NC3=C2C=CN3

Molecular Formula

C20H33N5

Molecular Weight

343.51

References & Citations

[1]Li T, Zhou Y, Fu X, et al. Identification of novel 4-substituted 7H-pyrrolo[2,3-d]pyrimidine derivatives as new FtsZ inhibitors: Bioactivity evaluation and computational simulation. Bioorg Chem. 2024;150:107534.