GS-443902 (trisodium)
GS-443902 trisodium (GS-441524 triphosphate trisodium) is a potent viral RNA-dependent RNA-polymerases (RdRp) inhibitor with IC50s of 1.1 μM, 5 μM for RSV RdRp and HCV RdRp, respectively. GS-443902 trisodium is the active triphosphate metabolite of Remdesivir (GS-5734) [1][2].
Product Specifications
CAS Number
1355050-21-3
Product Name Alternative
GS-441524 triphosphate (trisodium) ; Remdesivir metabolite (trisodium)
UNSPSC
12352005
Target
DNA/RNA Synthesis; Drug Metabolite; HCV; RSV; SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/gs-443902-trisodium.html
Purity
99.98
Solubility
H2O : 33.33 mg/mL (ultrasonic)
Smiles
O=P(OP(O)(O[Na])=O)(O[Na])OP(OC[C@@H](O1)[C@@H](O)[C@@H](O)[C@]1(C#N)C2=CC=C3N2N=CN=C3N)(O[Na])=O
Molecular Formula
C12H13N5Na3O13P3
Molecular Weight
597.15
References & Citations
Shipping Conditions
Dry Ice
Storage Conditions
-80°C, protect from light, stored under nitrogen
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Citation 01
Available Sizes
Frequently Asked Questions
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