Sempervirine
Sempervirine is an indole alkaloid isolated from Gelsemium sempervirens with anti-tumor activities. Sempervirine is against sempervirine-sensitive tumor cells with EC50 values of 2.7 μM, 1.77 μM, and 1.96 μM for Raji, MDA-MB-231 and HeLa cells, respectively[2].
Product Specifications
CAS Number
[549-92-8]
UNSPSC
12352005
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sempervirine.html
Solubility
10 mM in DMSO
Smiles
C1([N-]C2=C3C=CC=C2)=C3C=C[N+]4=CC5=C(CCCC5)C=C41
Molecular Formula
C19H16N2
Molecular Weight
272.34
References & Citations
[1]Noriyuki Kogure, et al. Total synthesis and full NMR assignment of ourouparine, a yohimbane-type indole alkaloid isolated from Gelsemium sempervirens. Journal of Natural Medicines volume
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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