Sempervirine
Sempervirine is an indole alkaloid isolated from Gelsemium sempervirens with anti-tumor activities. Sempervirine is against sempervirine-sensitive tumor cells with EC50 values of 2.7 μM, 1.77 μM, and 1.96 μM for Raji, MDA-MB-231 and HeLa cells, respectively[2].
Product Specifications
CAS Number
549-92-8
UNSPSC
12352005
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sempervirine.html
Solubility
10 mM in DMSO
Smiles
C1([N-]C2=C3C=CC=C2)=C3C=C[N+]4=CC5=C(CCCC5)C=C41
Molecular Formula
C19H16N2
Molecular Weight
272.34
References & Citations
[1]Noriyuki Kogure, et al. Total synthesis and full NMR assignment of ourouparine, a yohimbane-type indole alkaloid isolated from Gelsemium sempervirens. Journal of Natural Medicines volume
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
bsm-62653R-BF555-01 20 µL
EXOC3 Recombinant Antibody, AbBy Fluor™ 555 Conjugated
Sign In for Pricing
View Details bsm-62653R-BF555-02 100 µL
EXOC3 Recombinant Antibody, AbBy Fluor™ 555 Conjugated
Sign In for Pricing
View Details MBS8528815-02 0.1 mL (AF635)
Gamma Tubulin Mouse Monoclonal Antibody (4A4)
Sign In for Pricing
View Details MBS8528815-03 0.1 mL (AF610)
Gamma Tubulin Mouse Monoclonal Antibody (4A4)
Sign In for Pricing
View Details