Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Ajugol (Standard)

Ajugol (Standard) is the analytical standard of Ajugol. This product is intended for research and analytical applications. Ajugol is an orally active iridoid glycoside found in the traditional Chinese medicine Leonurus japonicus. Ajugol is an autophagy activator. Ajugol activates TFEB-mediated autophagy and lysosomal biogenesis. Ajugol also has anti-inflammatory effects. Ajugol has great potential in the research of asthma, non-alcoholic fatty liver disease (NAFLD), and osteoarthritis[1][2][3][4].

Product Specifications

CAS Number

52949-83-4

UNSPSC

12352005

Target

Autophagy; Interleukin Related; mTOR; Parasite; Reactive Oxygen Species (ROS) ; Reference Standards

Type

Reference Standards

Related Pathways

Anti-infection; Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others; PI3K/Akt/mTOR

Field of Research

Infection; Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/ajugol-standard.html

Smiles

O[C@H]1[C@](O[C@H](CO)[C@@H](O)[C@@H]1O)([H])O[C@H](OC=C2)[C@@]3([H])[C@]2([H])[C@H](O)C[C@@]3(O)C

Molecular Formula

C15H24O9

Molecular Weight

348.35

References & Citations

[1]Deniz Tasdemir, et al. Anti-protozoal and plasmodial FabI enzyme inhibiting metabolites of Scrophularia lepidota roots. Phytochemistry. 2005 Feb;66 (3) :355-62.|[2]Wu J, et al. Ajugol's upregulation of TFEB-mediated autophagy alleviates endoplasmic reticulum stress in chondrocytes and retards osteoarthritis progression in a mouse model. Chin Med. 2023 Sep 7;18 (1) :113.|[3]Zhang H, et al. Ajugol enhances TFEB-mediated lysosome biogenesis and lipophagy to alleviate non-alcoholic fatty liver disease. Pharmacol Res. 2021 Dec;174:105964.|[4]Yi L, et al.A novel iridoid glycoside leonuride (ajugol) attenuates airway inflammation and remodeling through inhibiting type-2 high cytokine/chemokine activity in OVA-induced asthmatic mice. Phytomedicine. 2022 Oct;105:154345.|[5]Xue B, et al. Pharmacokinetics and tissue distribution of Aucubin, Ajugol and Catalpol in rats using a validated simultaneous LC-ESI-MS/MS assay. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 1;1002:245-53.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

MAP1LC3A Recombinant Rabbit Monoclonal Antibody [SN07-40]
ET1611-37 100 µL

MAP1LC3A Recombinant Rabbit Monoclonal Antibody [SN07-40]

Sign In for Pricing
View Details
Human ADCY6 activation kit by CRISPRa
GA100074 1 Kit

Human ADCY6 activation kit by CRISPRa

Sign In for Pricing
View Details
LOC102641613 Mouse Monoclonal Antibody [Clone ID: 34-5-8S]
CL053F 100 µg

LOC102641613 Mouse Monoclonal Antibody [Clone ID: 34-5-8S]

Sign In for Pricing
View Details
Siglec 7 (SIGLEC7) Rabbit Polyclonal Antibody
AP11630PU-N 400 µL

Siglec 7 (SIGLEC7) Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
P21WAF1 (Tumor Suppressor Protein) (CIP1/2275R), CF647 conjugate, 0.1mg/mL
BNC472275-100 1x 100 µL

P21WAF1 (Tumor Suppressor Protein) (CIP1/2275R), CF647 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Nuclear Antigen (Pan-Nuclear Marker) (NM2984R), CF594 conjugate, 0.1mg/mL
BNC942984-500 1x 500 µL

Nuclear Antigen (Pan-Nuclear Marker) (NM2984R), CF594 conjugate, 0.1mg/mL

Sign In for Pricing
View Details