GPR109 receptor agonist-1

GPR109 receptor agonist-1 (Compound 3a) is a highly selective agonist of the human orphan G-protein-coupled receptor GPR109b, with the pEC50 of 6.4. GPR109 receptor agonist-1 can be used for the research of cardio-metabolic diseases[1].

Product Specifications

CAS Number

[306935-41-1]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

GPR109A

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cardiovascular Disease; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/gpr109-receptor-agonist-1.html

Purity

99.94

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C(N(C(C)C)N=N2)C2=C1)O

Molecular Formula

C10H11N3O2

Molecular Weight

205.22

Precautions

H315, H319, H335

References & Citations

[1]Graeme Semple, et al. 1-Alkyl-benzotriazole-5-carboxylic acids are highly selective agonists of the human orphan G-protein-coupled receptor GPR109b. J Med Chem. 2006 Feb 23;49 (4) :1227-30.