CPP-115
Product Specifications
UNSPSC Description
CPP-115 is a GABA transaminase inactivator with higher affinity and lower retinal toxicity than Vigabatrin (HY-15399). CPP-115 increases brain GABA levels by inhibiting GABA transaminase catabolism. CPP-115 can be used in the study of drug addiction and infantile spasms[1].
Target Antigen
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cpp-115.html
Smiles
OC([C@H]1C/C([C@H](C1)N)=C(F)\F)=O
Molecular Weight
177.15
References & Citations
[1]Silverman R B, et al. The 2011 EB Hershberg Award for important discoveries in medicinally active substances:(1 S, 3 S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115), a GABA aminotransferase inactivator and new treatment for drug addiction and infantile spasms[J]. Journal of medicinal chemistry, 2012, 55(2): 567-575.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-116910/CPP-115-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-116910/
Clinical Information
Phase 1
CAS Number
640897-20-7
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