LG100754
Product Specifications
UNSPSC Description
LG100754 (UVI 2112) is a RXR dimers modulater. LG100754 acts as a RXR:RXR homodimer antagonist, but functions as a agonist towards RXR:PPARα and RXR:PPARγ heterodimers. LG100754 is an insulin sensitizer that functions through RXR[1].
Target Antigen
RAR/RXR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/lg100754.html
Purity
99.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C/C(C1=C(OCCC)C=C2C(C)(C)CCC(C)(C)C2=C1)=C/C=C/C(C)=C/C(O)=O
Molecular Weight
396.56
References & Citations
[1]Cesario RM, et al. The rexinoid LG100754 is a novel RXR:PPARgamma agonist and decreases glucose levels in vivo. Mol Endocrinol. 2001 Aug;15(8):1360-9.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-108523/LG100754-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-108523/LG100754-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
180713-37-5
Available Sizes
Curated Selection
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