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(R) -Posenacaftor (sodium)

Selected Variant

HY-109187B-01

Size: 5 mg

(R) -Posenacaftor (R) -PTI-801) sodium is the R enantiomer of Posenacaftor. Posenacaftor is a cystic fibrosis transmembrane regulator (CFTR) protein modulator that corrects the folding and trafficking of CFTR protein. Posenacaftor is used for the research of cystic fibrosis (CF) [1].

Product Specifications

CAS Number

2095064-09-6

Product Name Alternative

(R) -PTI-801 (sodium)

UNSPSC

12352005

Target

CFTR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/r-posenacaftor-sodium.html

Purity

98.96

Solubility

DMSO : 38.33 mg/mL (ultrasonic)

Smiles

O=C(C1=CC(C2=C(C)C3=CC=CC=C3O2)=NC4=C(C)C=CC(O[C@@H](C)C5CCOCC5)=C14)O[Na]

Molecular Formula

C27H26NNaO5

Molecular Weight

467.49

References & Citations

[1]Benjamin Kopp, et al. Compositions et procédés pour améliorer la fonction cftr dans des cellules affectées par la fibrose kystique. Patent WO2019156946.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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