(R)-Posenacaftor (sodium)
Product Specifications
UNSPSC Description
(R)-Posenacaftor (R)-PTI-801) sodium is the R enantiomer of Posenacaftor. Posenacaftor is a cystic fibrosis transmembrane regulator (CFTR) protein modulator that corrects the folding and trafficking of?CFTR?protein. Posenacaftor is used for the research of cystic fibrosis (CF)[1].
Target Antigen
CFTR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/r-posenacaftor-sodium.html
Purity
98.96
Solubility
DMSO : 38.33 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(C2=C(C)C3=CC=CC=C3O2)=NC4=C(C)C=CC(O[C@@H](C)C5CCOCC5)=C14)O[Na]
Molecular Weight
467.49
References & Citations
[1]Benjamin Kopp, et al. Compositions et procédés pour améliorer la fonction cftr dans des cellules affectées par la fibrose kystique. Patent WO2019156946.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-109187B/R-Posenacaftor-sodium-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-109187B/R-Posenacaftor-sodium-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2095064-09-6
Available Sizes
Curated Selection
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