What is the catalog number for Arctiin?

The catalog number for Arctiin is HY-N0034.

What sizes are available for Arctiin?

Arctiin is available in the following size(s): 50 mg, 10 mM - 1 mL, 100 mg.

How many pack sizes does Arctiin come in?

Arctiin is available in 3 different pack sizes.

Arctiin is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Arctiin?

Arctiin is manufactured by QuantiMol.

What is the estimated delivery time for Arctiin?

Estimated delivery time for Arctiin is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Arctiin?

The safety data sheet for Arctiin is available here: http://file.medchemexpress.com/batch_PDF/HY-N0034/Arctiin-SDS-MedChemExpress.pdf.

Arctiin

Arctiin is an orally active inhibitor of NF-κB. Arctiin suppresses cyclin D1 protein expression in human tumor cells. Arctiin also reduces malondialdehyde and pro-in ammatory cytokines levels. Arctiin can used in study glomerulonephritis[4][6].

Product Specifications

CAS Number

20362-31-6

Product Name Alternative

Arctii; NSC 315527; Arctigenin-4-glucoside

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

NF-κB

Type

Natural Products

Related Pathways

NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Arctiin.html

Purity

99.52

Solubility

DMSO : 200 mg/mL (ultrasonic) |H2O : 10 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O[C@H]1[C@H](O)[C@@H](CO)O[C@@H](OC2=C(OC)C=C(C[C@H]3C(OC[C@@H]3CC4=CC(OC)=C(OC)C=C4)=O)C=C2)[C@@H]1O

Molecular Formula

C27H34O11

Molecular Weight

534.55

Precautions

H302, H315, H319, H335

References & Citations

[1]Huang DM, et al. Modulation of anti-adhesion molecule MUC-1 is associated with arctiin-induced growth inhibition in PC-3 cells. Prostate. 2004 May 15;59 (3) :260-7.|[2]Knipping K, et al. In vitro and in vivo anti-allergic effects of Arctium lappa L. Exp Biol Med (Maywood) . 2008 Nov;233 (11) :1469-77.|[3]Zeng Y, et al. Lack of significant modifying effect of arctiin on prostate carcinogenesis in probasin/SV40 T antigen transgenic rats. Cancer Lett. 2005 May 26;222 (2) :145-51.|[4]Wu JG, et al. Ameliorative effects of arctiin from Arctium lappa on experimental glomerulonephritis in rats. Phytomedicine. 2009 Nov;16 (11) :1033-41.|[5]Ma ST, et al. Effect of arctiin on glomerular filtration barrier damage in STZ-induced diabetic nephropathy rats. Phytother Res. 2013 Oct;27 (10) :1474-80.|[6]Matsuzaki Y, et al. Arctiin induces cell growth inhibition through the down-regulation of cyclin D1 expression. Oncol Rep. 2008 Mar;19 (3) :721-7.