C30 (ω-hydroxy) Ceramide (d18:1/30:0)

C30 (ω-hydroxy) Ceramide (d18:1/30:0), a sphingolipid, is an epidermis-specifically vital component of the water barrier in mammalian skin. C30 (ω-hydroxy) Ceramide (d18:1/30:0) is expressed in epidermal keratinocytes and male germ cells during their differentiation and maturation. C30 (ω-hydroxy) Ceramide (d18:1/30:0) deficiency in the epiderm of Elovl4 deletion or mutation mice[1][2].

Product Specifications

CAS Number

[457100-08-2]

UNSPSC

12352211

Target

Others

Type

Natural Products

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/c30-ω-hydroxy-ceramide-d18-1-30-0.html

Solubility

10 mM in DMSO

Smiles

O=C(N[C@@H](CO)[C@H](O)/C=C/CCCCCCCCCCCCC)CCCCCCCCCCCCCCCCCCCCCCCCCCCCCO

Molecular Formula

C48H95NO4

Molecular Weight

750.27

References & Citations

[1]Jennemann R, et al. Integrity and barrier function of the epidermis critically depend on glucosylceramide synthesis. J Biol Chem. 2007 Feb 2;282 (5) :3083-94.|[2]Sandhoff R. Very long chain sphingolipids: tissue expression, function and synthesis. FEBS Lett. 2010 May 3;584 (9) :1907-13.