PROTAC SMARCA2/4-degrader-27
PROTAC SMARCA2/4-degrader-27 (PROTAC 2) is a PROTAC-based degrader of SMARCA2 and SMARCA4. (Blue: CRL2VHL ligand VH032-cyclopropane-F (HY-125905) ; Black: linker (HY-159678) ; Pink: a SMARCA-BD ligand 1 for PROTAC (HY-44012) ) [1].
Product Specifications
UNSPSC
12352211
Target
Epigenetic Reader Domain; PROTACs
Type
Reference compound
Related Pathways
Epigenetics; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-smarca2-4-degrader-27.html
Smiles
O=C(C1(CC1)F)N[C@@H](C(C)(C)C)C(N2[C@@H](C[C@H](C2)O)C(NCC3=C(C=C(C4=C(C)N=CS4)C=C3)OCCC5=CC=C(C=C5)CN6CCN(C7=C(N)N=NC(C8=C(C=CC=C8)O)=C7)CC6)=O)=O
Molecular Formula
C49H58FN9O6S
Molecular Weight
920.10
References & Citations
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162834/PROTAC-SMARCA2-4-degrader-27-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162834/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
CAS Number
[2375564-54-6]
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