1,3-Dicyclohexylurea
1,3-Dicyclohexylurea (DCU) is an orally active and potent sEH (soluble epoxide hydrolase) inhibitor. Oral Delivery of 1,3-Dicyclohexylurea nanosuspension enhances exposure and lowers blood pressure in hypertensive Rats[1].
Product Specifications
CAS Number
[2387-23-7]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Epoxide Hydrolase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/1-3-dicyclohexylurea.html
Purity
99.85
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C) |Ethanol : ≥ 2.5 mg/mL
Smiles
O=C(NC1CCCCC1)NC2CCCCC2
Molecular Formula
C13H24N2O
Molecular Weight
224.35
Precautions
H302, H315, H319, H335
References & Citations
[1]Ghosh S, et al. Oral delivery of 1,3-dicyclohexylurea nanosuspension enhances exposure and lowers blood pressure in hypertensive rats. Basic Clin Pharmacol Toxicol. 2008 May;102 (5) :453-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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