1,3-Dicyclohexylurea

1,3-Dicyclohexylurea (DCU) is an orally active and potent sEH (soluble epoxide hydrolase) inhibitor. Oral Delivery of 1,3-Dicyclohexylurea nanosuspension enhances exposure and lowers blood pressure in hypertensive Rats[1].

Product Specifications

CAS Number

[2387-23-7]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Epoxide Hydrolase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/1-3-dicyclohexylurea.html

Purity

99.85

Solubility

DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C) |Ethanol : ≥ 2.5 mg/mL

Smiles

O=C(NC1CCCCC1)NC2CCCCC2

Molecular Formula

C13H24N2O

Molecular Weight

224.35

Precautions

H302, H315, H319, H335

References & Citations

[1]Ghosh S, et al. Oral delivery of 1,3-dicyclohexylurea nanosuspension enhances exposure and lowers blood pressure in hypertensive rats. Basic Clin Pharmacol Toxicol. 2008 May;102 (5) :453-8.