HE4, Human ascites fluid

HE4 belongs to the family of whey acidic four-disulfide core (WFDC) proteins with suspected trypsin inhibitor properties. The HE4 is a 13kD protein, although in its mature glycosylated form the protein is approximately 20-25 kD, and consists of a single peptide. It is one of the emerging co-marker for ovarian cancer.