LP99
LP99 is an inhibitor of BRD9 and BRD7 bromodomains. LP99 inhibits the interactions of both BRD7 and BRD9 with histones H3.3 and H4, with IC₅₀ values in the low micromolar range in bioluminescence resonance energy transfer (BRET) assays in HEK293 cells. It also inhibits IL-6 secretion from LPS stimulated THP-1 cells at a concentration of 10 μM.
Product Specifications
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36 months
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