StemBoost™ Reprogramming Cocktail, VCRFBI, Sterile-Filtered (100X)

StemBoost™ Reprogramming Cocktail, VCRFBI (100X), is a convenient, sterile-filtered cocktail solution (100X, in DMSO) for the generation of human neuronal cells from adult astrocytes. The cocktail contains the following five small molecules: CHIR99021 (Cat. No. 1677), a GSK-3β inhibitor, 300 μM; RepSox (Cat. No. 1894), a TGFβ inhibitor, 0.1 mM; Forskolin (Cat. No. 1531), a cAMP activator, 1.0 mM; I-BET151 (Cat. No. 2220), a BET bromodomain inhibitor, 200 μM; ISX9 (Cat. No. 2563), a neurogenic differentiation inducer, 1 mM. Also provided separately is a sterile-filtered solution (100X, in DI water) of the HDAC inhibitor Valproic Acid Sodium Salt (Cat. No. 1647), (50 mM).