JFD00244
JFD00244 is an inhibitor of SIRT2. SIRT2 is a NAD+ (nicotinamide adenine dinucleotide)-dependent deacetylase. A major substrate of SIRT2 is α-tubulin. JFD00244 inhibits SIRT2 with an IC₅₀ of 56.7 µM. It induces granulocytic differentiation in the acute promyelocytic leukemia cell line NB4 at a concentration of 5 μM.
Product Specifications
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36 months
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6297233-01 0.2 mL
EYA1, NT (EYA1, Eyes absent homolog 1) (Azide free) (HRP)
Sign In for Pricing
View Details