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Tenovin-6

Tenovin-6 is a SirT2 inhibitor and a p53 activator. It is a water-soluble analog of Tenovin-1. Tenovins inhibit the protein-deacetylase activities of SirT1 and SirT2. The IC₅₀ for inhibiting human SirT1 and SirT2 peptide deacetylase activity is 21 μM and 10 μM respectively. Tenovin-6 potently inhibits the proliferation of diffuse large B-cell lymphoma (DLBCL) and acute lymphoblastic leukemia cells.

Product Specifications

Shipping Conditions

RT

Storage Conditions

-20ºC

Shelf Life

36 months

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