Question 1

What is the catalog number for JGB1741?

Accepted Answer

The catalog number for JGB1741 is B2804-5.

Question 2

Is JGB1741 in stock?

Accepted Answer

JGB1741 is currently made to order / not held in immediate stock. Contact us for lead time.

Question 3

What is JGB1741 used for?

Accepted Answer

JGB1741 is a small molecule inhibitor of SIRT1. The sirtuins (SIRTs) are NAD+-dependent histone deacetylases. The IC₅₀ value of JGB1741 in a cell-free assay is 15 μM. The IC₅₀ for cell proliferation of three cancer cell lines, K562, HepG2 and MDA-MB 231 is 1 μM, 10 μM and 0.5 μM, respectively. JGB17

Question 4

Can this product be used for co-immunoprecipitation (Co-IP)?

Accepted Answer

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Question 5

Is this kit compatible with automated liquid handling platforms?

Accepted Answer

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

Question 6

What applications has this product been validated for?

Accepted Answer

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

JGB1741

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