nor-NOHA acetate

nor-NOHA acetate is a potent, reversible inhibitor of rat liver arginase with a Ki value of 0.5 µM, which is 20-fold lower than the Ki of 10 µM observed for NOHA. Nor-NOHA is about 40-fold more potent than NOHA as an inhibitor of arginase from mouse macrophages, displaying an IC₅₀ of 10-12 µM.