RU-521
RU-521 (RU-320521) is a potent, selective cyclic GMP-AMP synthase (cGAS) inhibitor (Kd = 36.2 nM). RU-521 is active and selective in cellular assays of cyclic GMP-AMP synthase-mediated signaling and reduces constitutive expression of interferon in macrophages from a mouse model of Aicardi-Goutières syndrome.
Product Specifications
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months
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