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MK-591 sodium salt

MK-0591 sodium is a potent and specific 5-Lipoxygenase-activating protein (FLAP) inhibitor with an IC₅₀ of 1.6 nM in FLAP binding assay; it displays no inhibitory effect on 15-lipoxygenase and platelet 12-lipoxygenase and cyclooxygenase in human PMNLs; potently inhibits leukotriene (LT) biosynthesis in intact human and elicited rat PMNLs with IC₅₀ of 3.1 and 6.1 nM, respectively.

Product Specifications

Shipping Conditions

Gel Pack

Storage Conditions

-20ºC

Shelf Life

36 months

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