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GSK-2190915 sodium salt

GSK-2190915 sodium is a potent and selective FLAP (5-Lipoxygenase-activating protein) inhibitor (IC₅₀ of 2.6 nM); displays good selectivity over CYP3A4, 2C9, and 2D6. In an acute inflammation setting, GSK-2190915 dose-dependently reduces LTB4, CysLTs, plasma protein extravasation and neutrophil influx induced by peritoneal zymosan injection.

Product Specifications

Shipping Conditions

Gel Pack

Storage Conditions

-20ºC

Shelf Life

36 months

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