Question 1

What is the catalog number for PFK-158?

Accepted Answer

The catalog number for PFK-158 is B2515-5.

Question 2

Is PFK-158 in stock?

Accepted Answer

PFK-158 is currently made to order / not held in immediate stock. Contact us for lead time.

Question 3

What is PFK-158 used for?

Accepted Answer

PFK158 is an inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3; IC₅₀ = 137 nM for human recombinant PFKFB3). Upon administration, PFK-158 binds to and inhibits the activity of PFKFB3, which leads to the inhibition of both the glycolytic pathway in and glucose uptake by canc

Question 4

What is the molecular weight of the target protein?

Accepted Answer

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

Question 5

How long will it take to receive this product if it’s custom made?

Accepted Answer

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

Question 6

What is the recommended dilution for this antibody?

Accepted Answer

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

PFK-158

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