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AZD-3229

AZD3229 is a potent, pan-KIT mutant inhibitor that displays single digit nM growth inhibition against a diverse panel of mutant KIT driven Ba/F3 cell lines (GI50=1-50 nM). It also inhibits PDGFR mutants (Tel-PDGFRα, Tel-PDGFRβ, V561D/D842V). Potentially could be useful for the treatment of gastrointestinal stromal tumors.

Product Specifications

Shipping Conditions

Gel Pack

Storage Conditions

-20ºC

Shelf Life

36 months

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