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CEP-40783

CEP-40783 (RDX-106) is a potent and selective inhibitor of AXL and c-Met with IC₅₀ values of 7 nM and 12 nM, respectively. In AXL-transfected 293GT cells, CEP-40783 was 27-fold more active compared to recombinant enzyme with an IC50 value of 0.26 nM. CEP-40783 displays potent AXL and c-Met pharmacodynamic and anti-tumor efficacy in established tumor xenograft models.

Product Specifications

Shipping Conditions

Gel Pack

Storage Conditions

-20ºC

Shelf Life

36 months

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