Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

UT-B-IN-1

UT-B-IN-1 (UTBINH-14) is a reversible, competitive and selective urea transporter-B (UT-B) inhibitor with IC50 values of 10 and 25 nM for human and mouse UT-B, respectively. UT-B-IN-1 shows low toxicity and high selectivity for UT-B over UT-A isoforms. UT-B-IN-1 increases urine output and reduces urine osmolality of mice. UT-B-IN-1 can be used for diuretic mechanism research[1].

Product Specifications

CAS Number

892742-76-6

UNSPSC

12352005

Target

Urea Transporter

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/ut-b-in-1.html

Purity

99.68

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=S(C1=C2N=C(NCC3=CC=CS3)C4=C(C=CS4)N2N=N1)(C5=CC=C(CC)C=C5)=O

Molecular Formula

C20H17N5O2S3

Molecular Weight

455.58

References & Citations

[1]Yao C, et al. Triazolothienopyrimidine inhibitors of urea transporter UT-B reduce urine concentration. J Am Soc Nephrol. 2012 Jul;23 (7) :1210-20.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

tert-Butylamine
TRC-B690775-50ML 50 mL

tert-Butylamine

Sign In for Pricing
View Details
FITC Conjugated Solanum tuberosum (Potato) -STA-
F-4701-2 2 mg

FITC Conjugated Solanum tuberosum (Potato) -STA-

Sign In for Pricing
View Details
LRRC50 (DNAAF1) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI3F9]
TA504574BM 100 µL

LRRC50 (DNAAF1) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI3F9]

Sign In for Pricing
View Details
Deoxyribonuclease I like 1 (DNASE1L1) Rabbit Polyclonal Antibody
TA370121 100 µL

Deoxyribonuclease I like 1 (DNASE1L1) Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
PEDF (SERPINF1) (NM_002615) Human Over-expression Lysate
LC400927 20 µg

PEDF (SERPINF1) (NM_002615) Human Over-expression Lysate

Sign In for Pricing
View Details
N-Nitrosodiisopropylamine- d14
TRC-N525602-10MG 10 mg

N-Nitrosodiisopropylamine- d14

Sign In for Pricing
View Details