Question 1

What is the catalog number for PF-04449913?

Accepted Answer

The catalog number for PF-04449913 is B2467-5.

Question 2

Is PF-04449913 in stock?

Accepted Answer

PF-04449913 is currently made to order / not held in immediate stock. Contact us for lead time.

Question 3

What is PF-04449913 used for?

Accepted Answer

PF-04449913 is a potent and orally bioavailable smoothened (SMO) inhibitor. PF-04449913 binds to human SMO with an IC₅₀ of 4 nM. It has been shown to attenuate leukemia stem cell self-renewal and cell cycle progression in primary acute myeloid leukemia cells and in an in vivo Drosophila model.

Question 4

What is the recommended positive control for this assay?

Accepted Answer

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

Question 5

How should this product be stored?

Accepted Answer

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Question 6

Is this product animal-origin-free?

Accepted Answer

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

PF-04449913

Product Specifications

Shipping Conditions

Storage Conditions

Shelf Life

Frequently Asked Questions

Explore Other Products

ST3GAL2 Protein Vector (Rat) (pPB-N-His)

SAR1B, ID (SAR1B, SARA2, SARB, GTP-binding protein SAR1b, GTP-binding protein B) (MaxLight 405)

SAR1B, ID (SAR1B, SARA2, SARB, GTP-binding protein SAR1b, GTP-binding protein B) (MaxLight 405)

CDH16, CT (CDH16, Cadherin-16, Kidney-specific cadherin) (Biotin)

CDH16, CT (CDH16, Cadherin-16, Kidney-specific cadherin) (Biotin)

Anti-PRCC Antibody Picoband® HRP Conjugated