HDM-201
Siremadlin (NVP-HDM201) is a potent and highly specific MDM-2/p53 inhibitor. It binds to human MDM2 protein with a picomolar Ki value (0.21 nM). It activates p53 and induces robust p53-dependent cell cycle arrest and apoptosis in human p53 wild-type tumor cells.
Product Specifications
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months
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