AHR rabbit pAb
The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as Cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes. [provided by RefSeq, Sep 2015],
Product Specifications
Background
Gene ID
196
UniProt
P35869
Cellular Locus
Cytoplasm. Nucleus. Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus..
Host
Rabbit
Species Reactivity
Human,Mouse,Rat,Fish
Reactivity
Human; Mouse; Rat; Fish
Immunogen
Synthesized peptide derived from human AHR AA range: 408-458
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IF
Validated Applications
WB,IF
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000; IF/ICC 1:100-500
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES18432-1.pdf
Subcellular Location
Cytoplasm . Nucleus . Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus. .
Gene ID (Human)
196
SwissProt (Human)
P35869
Available Sizes
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