AHR rabbit pAb
The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as Cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes. [provided by RefSeq, Sep 2015],
Product Specifications
Background
UniProt
P35869
Swiss Prot
P35869
Reactivity
Human; Mouse; Rat; Fish
Immunogen
Synthesized peptide derived from human AHR AA range: 408-458
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IF
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IF/ICC 1:100-500
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Cytoplasm . Nucleus . Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus. .
Gene ID (Human)
196
Available Sizes
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