BMY 14802
BMY 14802 is a sigma-1 receptor (σ1R) antagonist, as well as an agonist at serotonin (5-HT) 1A and adrenergic alpha-1 receptors. BMY 14802 inhibits abnormal involuntary movement (AIM) in rat Parkinson's disease (PD) model, with down-regulating the expression of AIM[1][2].
Product Specifications
CAS Number
105565-56-8
UNSPSC
12352005
Target
5-HT Receptor; Adrenergic Receptor; Sigma Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bmy-14802.html
Concentration
10mM
Purity
98.96
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
FC1=CN=C(N2CCN(CCCC(C3=CC=C(C=C3)F)O)CC2)N=C1
Molecular Formula
C18H22F2N4O
Molecular Weight
348.39
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
MLAG-3; Sigma 1 Receptor; α adrenergic receptor
Available Sizes
Frequently Asked Questions
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