Poloxamer 182 (L62)

Poloxamer 182 (L62) can be used as an excipient, such as Emulsifier, solubilizer, lubricant, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1].

Product Specifications

CAS Number

[9003-11-6]

Product Name Alternative

PEG-PPG-PEG, 2500 (Average Mn)

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/poloxamer-182-l62.html

Solubility

10 mM in DMSO

Smiles

CC.[H(OCH2CH2)x(OCH2CH)y(OCH2CH2)zOH].[CH3]

Molecular Weight

2500 (Average)

Precautions

H302, H315, H319, H335

References & Citations

[1]Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.|[2]Carvalho GC, et al. Highlights in poloxamer-based drug delivery systems as strategy at local application for vaginal infections. Int J Pharm. 2021 Jun 1;602:120635.