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2-Hydroxybenzimidazole

2-Hydroxybenzimidazole is an inactive compound targeting CYP1A1 and is mainly used as a control compound in the structure-activity relationship study of benzimidazole derivatives. 2-Hydroxybenzimidazole does not have the ability to induce CYP1A1 expression like its thiol or amino substituted derivatives[1].

Product Specifications

CAS Number

615-16-7

UNSPSC

12352200

Hazard Statement

H302

Target

Cytochrome P450

Type

Biochemical Assay Reagents

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/2-hydroxybenzimidazole.html

Purity

99.98

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C1NC2=CC=CC=C2N1

Molecular Formula

C7H6N2O

Molecular Weight

134.14

Precautions

H302

References & Citations

[1]Backlund M, et al. Structural and mechanistic aspects of transcriptional induction of cytochrome P450 1A1 by benzimidazole derivatives in rat hepatoma H4IIE cells. Eur J Biochem. 1999 Apr;261 (1) :66-71.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Isoform

CYP1

Available Sizes

Frequently Asked Questions

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