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(Rac) -EC5026

(Rac) -EC5026 ((Rac) -BPN-19186) is a potent piperidine inhibitor of soluble epoxide hydrolase (sEH) extracted from patent WO2019156991A1, page 39, has a Ki of 0.06 nM. (Rac) -EC5026 can be used for the research of Parkinson's disease and dementia with Lewy Bodies (DLB) [1].

Product Specifications

CAS Number

1809885-55-9

Product Name Alternative

(Rac) -BPN-19186

UNSPSC

12352005

Target

Epoxide Hydrolase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/rac-ec5026.html

Purity

98.25

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(NC1CCN(C(C(C)CC)=O)CC1)NC2=CC=C(OC(F)(F)F)C(F)=C2

Molecular Formula

C18H23F4N3O3

Molecular Weight

405.39

References & Citations

[1]Hammock BD, et, al. Methods of inhibiting formation of alpha synuclein aggregates. WO2019156991A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 1

Available Sizes

Frequently Asked Questions

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