(Rac) -EC5026
(Rac) -EC5026 ((Rac) -BPN-19186) is a potent piperidine inhibitor of soluble epoxide hydrolase (sEH) extracted from patent WO2019156991A1, page 39, has a Ki of 0.06 nM. (Rac) -EC5026 can be used for the research of Parkinson's disease and dementia with Lewy Bodies (DLB) [1].
Product Specifications
CAS Number
[1809885-55-9]
Product Name Alternative
(Rac) -BPN-19186
UNSPSC
12352005
Target
Epoxide Hydrolase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/rac-ec5026.html
Purity
98.25
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(NC1CCN(C(C(C)CC)=O)CC1)NC2=CC=C(OC(F)(F)F)C(F)=C2
Molecular Formula
C18H23F4N3O3
Molecular Weight
405.39
References & Citations
[1]Hammock BD, et, al. Methods of inhibiting formation of alpha synuclein aggregates. WO2019156991A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
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